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| Quantity: | |
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| Quick Details |
Name | CAS No 128446-36-6（HP-Beta-CD) |
Place of Origin: | Shandong, China |
Type | Syntheses Material Intermediates |
Purity: | 99% |
Brand Name | Zhiyuan |
Application | Raw Materials |
Appearance | White powder |
pH | 5.0~7.5 |
Sample | Available |
Test Report | Available |
MOQ | 1kg |
Solubility | Water Soluble |
| Product Introduction |
Methylated beta cyclodextrin is an alkylated derivative of beta cyclodextrin. The hydrogen on C2, C3 and C6 hydroxyl groups of betacyclodextrin can be substituted by methyl. Methyl beta cyclodextrin is not only water-soluble, but also soluble in organic solvents, and has strong drug inclusion ability, so it has attracted attention in the field of pharmaceutical preparations. Methyl beta cyclodextrin does not accumulate in the body and is quickly excreted through the kidney.
Binzhou Zhiyuan biotechnology mainly produces methyl beta cyclodextrin, 2, 6-Dimethyl beta cyclodextrin.
Methyl cyclodextrin have good solubilization and inclusion ability. Their inclusion ability is usually greater than that of hydroxypropyl beta cyclodextrin, which is soluble in water and organic solvents. Therefore, they are widely used in medicine, pesticide, food, cosmetics, daily chemical products, textile dyeing and finishing, chemical industry, chromatographic materials or other materials science.
| Product Specification |
Specification Data Sheet of 128446-36-6（HP-Beta-CD) | |||
Raw material Origin | China | Manufacturing place | China |
ITEMS | criteria | METHOD OF ANALYSIS | |
Appearance | White or almost white powder;Odorless, slightly sweet;Freely soluble in water，soluble in methanol and ethanol. | Visual | |
Assay | ≥98% | CP2020 | |
Specific rotation | +154°~+165° | CP2020 | |
Clarity of Solution | 2.5g/25ml water solution is clear. | CP2020 | |
Light-absorbing impurities | Between 230 nm and 750 nm,the absorbance is not greater than 1.0; | CP2020 | |
Average Degree of Substitution | 7.0~13.3 | CP2020 | |
Loss on Drying | ≤7.0% | CP2020 | |
Beta Cyclodextrin | ≤0.2% | CP2020 | |
Residue on ignition | ≤0.5% | CP2020 | |
The total aerobic microbial count | ≤1000cfu/g | CP2020 | |
The total combined moulds and yeasts count | ≤100cfu/g | CP2020 | |
Escherichia coli | Absence | CP2020 | |
| Composition |
Composition of Methyl Beta Cyclodextrin | ||
Product name | Methyl Beta Cyclodextrin CAS No 128446-36-6 | |
Mixture | Yes | |
Chemical name | CAS No. | CONTENT（%） |
Methyl Cyclodextrin | 128446-36-6 | 98%-100% |
Loss on Drying | 7732-18-5 | 3%-7% |
| Application |
Methyl cyclodextrin is widely used in pharmaceutical, food, cosmetics, textiles and other industries.
Advantages:
Methyl cyclodextrin has a strong ability of inclusion of oil soluble molecules than other cyclodextrins.
FAQ |
Q: Is the company a division or subsidiary of another cooperation?
A: No,it isn’t.
Q: Can you provide an organizational chart!
A: Yes, we can.
Q: Does the company have adequate business license and drug production license complete?
A: Yes.
Q: Does the company provide the copies of certificates, licenses and other relevant documents?
A: Yes, we have.
Q: How many shifts of operation are there in the production area?
A: Three shifts.
Q: Is there a published quality
A: Yes, we have.
Q: Is the company approved to ISO series?(Give Registration Number)
A: GB/T 19001-2016/ISO 9001:2015 Certificate Number: 00223Q23864R1S
Production Process |
How to product Methyl beta cyclodextrin :
Methyl beta cyclodextrin was synthesized with dimethyl sulfate as alkylation reagent. Add 2g sodium hydroxide and 30ml deionized water into the flask, then add 10g beta cyclodextrin, and stir to dissolve.
Add 5ml dimethyl sulfate slowly at room temperature, stir at the same time, heat in water bath at about 60 ℃ for 8h, cool down after reaction, adjust to neutral with dilute hydrochloric acid, dilute the solution with appropriate amount of water, and then remove anions and cations in the solution with ion exchange resin (repeat 2-3 times). The collected liquid is distilled under reduced pressure, concentrated to syrup, and slowly dripped with 40ml acetone. The product is dispersed into powdery solid in acetone. The acetone is filtered and vacuum dried to obtain the product.
