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This technical-grade Hydroxypropyl Beta Cyclodextrin is a cyclodextrin derivative developed for inclusion complex formation. The introduction of hydroxypropyl groups breaks the intramolecular ring hydrogen bonds of native beta cyclodextrin, while fully retaining its hydrophobic cavity structure. This modification effectively addresses the low water solubility limitation of native beta cyclodextrin, enabling stable performance across a wide range of water-based industrial systems. As one of the most extensively studied and widely applied cyclodextrin derivatives with the CAS number 128446-35-5, this product supports consistent formulation results in industrial production and laboratory research. This technical-grade product is designed for industrial and laboratory reagent use, and is not intended for human consumption or pharmaceutical applications.
Item | Specification |
|---|---|
Name | (2-hydroxypropyl)-β-cyclodextrin |
CAS Number | 128446-35-5 |
Abbreviation | HPBCD |
Molecular Formula | C42H70-nO35(C3H7O)n |
Molecular Weight | 1134.98+58n |
Classification | Technical grade |
ITEMS | CRITERIA |
|---|---|
Appearance | This product is white or white amorphous or crystalline powder; odorless, slightly sweet; strong moisture absorption. It is very soluble in water, methanol or ethanol, and almost insoluble in acetone or trichloromethane. |
Identification | Purple ring should appear at the interface between two liquids. |
pH | 5.0-7.5 |
Betadex | ≤1.0% |
Water | ≤10.0% |
Residue on Ignition | ≤3.5% |
Heavy Metals | ≤20ppm |
Average Degree of Substitution | 4.0-6.0 |
Conductivity | ≤5000μS/cm |
Packaging and storage | Preserve in well-closed containers |
In textile processing workflows, HPBCD acts as a functional encapsulation additive for hydrophobic active components such as dyes and finishing agents. It also finds broad use in coating, sterol, and pigment formulations, as well as surfactant systems, improving the dispersion stability of hydrophobic ingredients in water-based systems and reducing formulation separation issues.
Applied in air purification systems and indoor environmental treatment solutions, HPBCD encapsulates volatile odorous compounds through its hydrophobic cavity, supporting odor reduction and air quality optimization in enclosed industrial and commercial spaces.
In agrochemical production, HPBCD enables inclusion of hydrophobic active pesticide ingredients, enhancing their water dispersibility and formulation stability during storage and application. For phytosterol processing, the nonpolar cavity of HPBCD provides suitable space for the nonpolar carbon chain segments of sterols, while the inherent hydroxyl groups of sterols remain exposed. Combined with the hydroxyl groups on the cyclodextrin backbone, this structure improves overall hydrophilicity and elevates the water solubility of phytosterols in aqueous formulation systems.
HPBCD is used for fragrance encapsulation in essence, spice and oral care product manufacturing. It supports controlled release of aromatic components, extending the effective duration of fragrance in finished products and reducing volatile loss during processing and storage.
On-demand pack sizes are available with no additional surcharge. Standard multi-kilogram pack options include 1kg, 5kg and 10kg. Inner packaging adopts PE bags and aluminum foil bags, while outer packaging is available in cartons or drums to meet different logistics and handling needs.
To maintain product physical and chemical properties, the product should be preserved in well-closed containers and protected from moisture during long-term storage and transportation.
The tariff number for this product is 3505100000, which can be referenced for customs declaration and commercial logistics arrangement.
HPBCD retains the complete hydrophobic cavity of native beta cyclodextrin, while the hydroxypropyl modification breaks intramolecular hydrogen bonds and greatly improves water solubility, expanding its applicability in water-based industrial formulations.
Under standard production testing protocols, the average degree of substitution of this product ranges from 4.0 to 6.0.
Standard pack sizes include 1kg, 5kg and 10kg. Customized pack sizes can also be provided on demand without extra surcharges.
The pH value of this product falls within 5.0-7.5, which is compatible with most neutral and weakly acidic industrial formulation systems.
