You are here: Home / Products / Cyclodextrin Reagent / Carboxymethyl Beta Cyclodextrin

Carboxymethyl Beta Cyclodextrin

When pH<4, Carboxymethyl-β-Cyclodextrin (CM-β-CD) solubility is low in water. But when pH>4, Carboxyl Group Dissociate, CM-β-CD solubility becomes higher. It is very good for controlled release.
Availability:
Quantity:
facebook sharing button
twitter sharing button
line sharing button
wechat sharing button
linkedin sharing button
pinterest sharing button
whatsapp sharing button
sharethis sharing button

Quick Details

Name

Carboxymethyl beta cyclodextrin

CAS No.

218269-34-2

Synonyms

Carboxymethyl-β-Cyclodextrin;

Carboxymethyl beta cyclodextrin sodium salt;

Molecular Formula

C42H70-nO35· (CH2COONa)n

Molecular Weight

1135.0+80 n
AppearanceWhite or light yellow powder, odorless 


Solubility

Solubility of Carboxymethyl beta cyclodextrin

Solvent

Water

Ethanol

Acetone

Ether

Methanol

DMF

Solubility

X<0.5ml

50mlX<500ml

X>5000ml

X>5000ml

X>5000ml

15mlX<50ml

Remark

X means solubility.

Temperature T=25 ,
Quantity of solvents: 0.5g.
Dissolve with the minimum amount of relevant reagents.

Note: (Temperature T=25 ℃) Take 0.5g of solute and dissolve it with the minimum amount of corresponding reagent.

Note: (Temperature T=25 ℃) Take 0.5g of solute and dissolve it with the minimum amount of corresponding reagent.

 

Slightly soluble: 15ml≤ X<50ml    Slightly soluble: 15ml ≤ X<50ml

Extremely soluble: X<0.5ml     Slightly soluble: 50ml ≤ X<500ml

Soluble: 0.5ml ≤ X<5ml          Very slightly soluble: 500ml ≤ X<5000ml

Dissolution: 5ml ≤ X<15ml        Insolubility: X>5000ml



Characteristic

Carboxymethyl beta Cyclodextrin (carboxymethyl- β- Cyclodextrin) has low solubility in low pH solutions, but can be dissolved in neutral and alkaline solutions (pH>4) at any concentration, and its structure is loose, and its self mobility is greatly improved. It has good solubility in the environment of human intestinal pH 6-7, and can be used as drug prolonging release agent. It has lower hemolysis than hydroxypropyl beta Cyclodextrin.


Application

[Purpose]:

As chiral selectivity (or mobile phase chiral additive), it is used for the analysis of chiral compounds by high performance liquid chromatography or high performance capillary electrophoresis. It can be mainly applied to the resolution of chiral drugs such as Paroxetine and its intermediates, Barbital, steroids, quinolones and some amino acids.

Shandong Binzhou Zhiyuan Biology is a high-tech enterprise specializing in the research and production of Cyclodextrin and its derivatives. Relying on the Cyclodextrin Research Center of Shandong University, it has a strong technical force. We are equipped with advanced detection equipment, such as meteorological chromatograph, high-performance liquid chromatography, ion chromatograph, capillary electrophoresis, infrared spectrometer, one thousandth balance, trace moisture detector, and other imported detection instruments. The inspection methods are complete and can provide mass spectrometry, carbon spectroscopy, infrared spectroscopy, and nuclear magnetic resonance, providing strong support for product quality control and development research. Reliable quality and favorable prices have been recognized by customers both domestically and internationally.


Packaging and Delivery

Packaging and Delivery

Shandong Binzhou Zhiyuan is committed to best customer services.

Can assurance of product quality and safety.

Can offer flexible packing options, such as 1g/ bottle, 2g/ bottle, 5g/ bottle, 10g/ bottle or or according to customers' request. Including g to kg package sizes.

Can accurate weighing service.

Storage : Indoor in a cool and ventilated place, sealed for storage.

Transportation method:via FEDEX, UPS, DHL etc.

Validity period: two years.


Previous: 
Next: 

Tel

+86-531-6310-3628

Address

Yinfeng International Biocity A7, Jinan, Shandong, China

ABOUT US

Jinan Xinzhiyuan Biotechnology Co., Ltd. is a high-tech enterprise specializing in new materials, including pharmaceutical excipients and cosmetic ingredients, relying on the support of Shandong Binzhou Zhiyuan Biotechnology Co., Ltd.

QUICK LINKS

PRODUCT CATEGORY

CONTACT US

Copyright © 2025 Jinan Xinzhiyuan Biotechnology Co., Ltd. All Rights Reserved.|SitemapPrivacy Policy