Mercapto Beta Cyclodextrin for Analytical Chemistry Research

Mercapto cyclodextrins are cyclodextrin derivatives functionalized with reactive thiol (-SH) groups. Retaining the native cyclodextrin structure with a hydrophobic internal cavity and hydrophilic outer surface, these molecules form host-guest inclusion complexes with various guest compounds. The thiol groups enable covalent attachment to gold surfaces and the assembly of ordered supramolecular structures. This product line covers α, β and γ configurations, available in both mono-substituted and per-substituted forms. It applies to analytical chemistry research, sensor development, nanomaterial engineering and targeted drug delivery systems. Custom synthesis is supported for quantities ranging from grams to kilograms.

Mercapto Cyclodextrin Product Specifications & Technical Parameters

Product Classification

Detailed Technical Parameters

ZY-R013

ZY-R014

ZY-R015

ZY-R016

Solubility Data

Remark: X means solubility. Test condition: temperature T=25 ℃, sample quantity: 0.5g. Dissolution is performed with the minimum amount of relevant reagents.

Core Properties of Mercapto Cyclodextrin

The thiol groups on the cyclodextrin backbone are reactive functional groups that undergo oxidation or substitution reactions, supporting the construction of higher-order supramolecular structures. Thiol groups have high affinity for gold surfaces, enabling stable covalent attachment for surface modification scenarios. These derivatives retain the host-guest inclusion capability of native cyclodextrins, encapsulating hydrophobic guest molecules within the internal cavity. This property supports solubility enhancement, molecular recognition and selective separation processes. Mercaptocyclodextrin derivatives also have established applications in the reversal of drug-induced neuromuscular anesthesia.

Industrial & Research Applications of Mercapto Cyclodextrin

In supramolecular chemistry, mercapto cyclodextrins act as reactive host molecules for assembling functional supramolecular systems, and can be grafted onto polymers to fabricate stimuli-responsive materials and structured molecular devices. In analytical chemistry, they serve as chiral selectors in chromatographic systems for enantiomeric separation of chiral compounds. They also support the fabrication of electrochemical and optical sensors via modification of gold electrode surfaces for targeted analyte detection. In drug delivery, these compounds form inclusion complexes with poorly soluble drugs, improving aqueous solubility and chemical stability of active ingredients to optimize pharmacokinetic performance. Additional applications include environmental remediation for heavy metal and organic pollutant removal, and nanomaterial engineering for gold nanoparticle surface functionalization.

Packaging, Storage & Delivery for Commercial Procurement

Standard packaging options include 1g, 2g, 5g and 10g per bottle. Custom packaging specifications are available on request, with sizes ranging from gram-scale to kilogram-scale. Accurate weighing services are provided for all orders. Products should be stored indoors in cool, ventilated conditions and kept in sealed containers. The validity period is two years under recommended storage conditions. Shipping is available via international carriers including FEDEX, UPS and DHL.

FAQ About Mercapto Cyclodextrin

What configurations of mercapto cyclodextrin are available?

We offer α, β and γ configurations, with both mono-substituted and per-substituted options. Each configuration corresponds to a standard item number with defined technical specifications.

What solubility data is available for mercapto cyclodextrin?

Solubility across six common solvents is listed in the technical parameters, tested at 25℃ with a 0.5g sample. The compound shows highest solubility in DMF and moderate solubility in water and ethanol.

Do you support custom synthesis for commercial orders?

Yes, custom synthesis is available for quantities from grams to kilograms. Packaging can be adjusted to match the requirements of industrial clients and research institutions.

What is the shelf life of mercapto cyclodextrin?

The product has a validity period of two years when stored in sealed packaging in a cool, ventilated environment as specified in the storage guidelines.