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Quick Details |
Name | Gamma cyclodextrin |
CAS Number | 17465-86-0 |
Molecular Formula | C48H80O40 |
Molecular Weight | 1297.12 |
Appearance | White or almost whiteamorphous or crystalline powder. |
Assay | 98%-102% |
| Classification | Pharmaceutical Grade |
| quality standard | Enterprise Standard |
Product Introduction |
γ-Cyclodextrin sometimes abbreviated as γ-CD, is an octasaccharidederived from glucose. The α- (alpha), β- (beta), and γ- (gamma) cyclodextrins correspond to six, seven, and eight glucose units, respectively.
Structure |
In γ-cyclodextrin, the eight glucose subunits are linked end to end via α-1,4 linkages. The result has the shape of a tapered cylinder, with 8 primary alcohols on one face and 16 secondary alcohol groups on the other. The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic.
Solubility |
γ-Cyclodextrin exists as a white (colorless) powder or crystals. The density of its hydrate crystal (γCD·14H2O) is 1.41 g/cm3. γ-Cyclodextrin is well soluble in water and dimethyl sulfoxide, poorly soluble in methanol.
Application |
In the field of Pharmaceutical:
Gamma cyclodextrin CAS 17465-86-0 is mainly used to increase the solubility and stability of drugs. Cyclodextrin inclusion compounds with hydrophobic molecules are able to penetrate human tissues and can be used to release bioactive compounds under specific conditions. Enhance the mucosal permeability of the drug.