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Gamma Cyclodextrin

Gamma Cyclodextrin has the largest cavity size then beta and alpha cyclodextrin, it is well-suited to accommodate larger biomolecules and other guests. So Gamma Cyclodextrin is most commonly used as a complexing agent. Gamma cyclodextrin CAS 17465-86-0 is widely used in food, cosmetics, textiles、pharmaceutical industries for the microencapsulation of sensitive fine chemicals.
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Quick Details

Name

Gamma cyclodextrin

CAS Number

17465-86-0

Molecular Formula

C48H80O40

Molecular Weight

1297.12

Appearance

White or almost whiteamorphous or crystalline powder.

Assay

98%-102%
ClassificationPharmaceutical Grade
quality standardEnterprise Standard


Product Introduction

γ-Cyclodextrin sometimes abbreviated as γ-CD, is an octasaccharidederived from glucose. The α- (alpha), β- (beta), and γ- (gamma) cyclodextrins correspond to six, seven, and eight glucose units, respectively.


Structure

In γ-cyclodextrin, the eight glucose subunits are linked end to end via α-1,4 linkages. The result has the shape of a tapered cylinder, with 8 primary alcohols on one face and 16 secondary alcohol groups on the other. The exterior surface of cyclodextrins is somewhat hydrophilic whereas the interior core is hydrophobic.


Solubility

γ-Cyclodextrin exists as a white (colorless) powder or crystals. The density of its hydrate crystal (γCD·14H2O) is 1.41 g/cm3. γ-Cyclodextrin is well soluble in water and dimethyl sulfoxide, poorly soluble in methanol.


Application

In the field of Pharmaceutical:

Gamma cyclodextrin CAS 17465-86-0 is mainly used to increase the solubility and stability of drugs. Cyclodextrin inclusion compounds with hydrophobic molecules are able to penetrate human tissues and can be used to release bioactive compounds under specific conditions. Enhance the mucosal permeability of the drug.


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