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60% Water-Soluble Azelaic Acid Skin Clarifying Cosmetic Preparations

Classified as FDA Pregnancy Category B, our 60% Water-Soluble Azelaic Acid offers a safe, effective solution for formulators targeting acne-prone and sensitive skin. The supramolecular encapsulation technology enhances skin permeability while reducing follicular hyperkeratosis through decreased filamentous keratin synthesis. With 55-65% assay range and pH 4.0-6.8, this versatile ingredient delivers antibacterial, anti-inflammatory, and skin-brightening benefits. It works seamlessly in anti-acne serums, whitening creams, and antioxidant skincare formulations for all skin types.
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Overview of 60% Water-Soluble Azelaic Acid

Product Identity & Composition

60% Water-Soluble Azelaic Acid is a cosmetic-grade active ingredient designed for skin clarifying formulations. Also known as NanoActive Azelaic Acid, this ingredient features azelaic acid (C₉H₁₆O₄) encapsulated within a water-soluble delivery system. The final product appears as a white or off-white powder with an active assay range of 55.0% to 65.0%. This form addresses the limited water solubility of raw azelaic acid, enabling easier incorporation into aqueous-based cosmetic products.

Supramolecular Encapsulation Technology

This ingredient utilizes supramolecular encapsulation technology to enhance azelaic acid delivery. Compared with simple azelaic acid-cyclodextrin inclusion complexes, the supramolecular approach achieves a higher active loading capacity within the same carrier system. This encapsulation method also supports improved skin permeability and helps maintain ingredient stability during formulation and storage.

Water-Soluble Azelaic Acid

Technical Specifications of Water-Soluble Azelaic Acid

ITEMS

criteria

Appearance

White or off white powder

Assay

55.0%-65.0%

Moisture

≤15%

Heavy Metal

≤10ppm

pH(5%)

4.0-6.8

Packaging and storage

Preserve in well-closed containers.

Skin Benefits & Mechanisms of Azelaic Acid

Antimicrobial & Anti-Acne Properties

Azelaic acid exhibits antimicrobial activity against Cutibacterium acnes, the bacterium associated with acne development. It also helps reduce follicular hyperkeratosis by decreasing filamentous keratin synthesis, which supports the unclogging of pores and reduces the formation of comedones. These properties make the ingredient suitable for formulations targeting acne-prone skin.

Pigmentation Regulation & Skin Brightening

Azelaic acid interferes with melanin synthesis by inhibiting tyrosinase enzyme activity. It also helps normalize the function of hyperactive melanocytes without affecting normally pigmented skin cells. This selective action supports the even-toning of skin and the reduction of hyperpigmentation, including post-inflammatory hyperpigmentation following acne lesions.

Keratinocyte Regulation & Barrier Support

Unlike some other exfoliating acids, azelaic acid works by normalizing keratinocyte proliferation rather than causing aggressive desquamation. This mechanism contributes to smoother skin texture with a lower risk of irritation. The pH range of 4.0 to 6.8 also aligns with the skin's natural acidic mantle, supporting compatibility with the skin barrier.

Applications in Cosmetic Formulations

60% Water-Soluble Azelaic Acid can be incorporated into various cosmetic product types. Common applications include anti-acne serums and treatments, skin brightening creams and lotions, antioxidant skincare formulations, and products for sensitive or reactive skin types. Its water-soluble form allows for use in both serums and cream-based products.

Formulation Guidelines

This ingredient is compatible with aqueous systems and can be added during the water phase of emulsion production. The pH range of 4.0 to 6.8 provides flexibility across different formulation types. Formulators typically adjust usage levels based on the desired product profile and target skin concern. The powder form allows for easy weighing and incorporation during manufacturing.

Packaging, Storage & Supply Information

Packaging Specifications

The product is available in multiple packaging sizes to accommodate different production scales. Standard options include 1kg/bag, 2kg/bag, and 10kg/drum. Inner packaging consists of a PE bag with an additional aluminum foil bag for moisture protection. Outer packaging uses fiber drums for 10kg units. Custom labeling options are available for commercial procurement orders.

Storage & Shelf Life

60% Water-Soluble Azelaic Acid should be preserved in well-closed containers. Proper storage conditions help maintain ingredient potency and prevent moisture absorption. The product is manufactured under controlled conditions and undergoes quality testing before release, including verification of assay, pH, moisture content, and heavy metal limits.

FAQ About Water-Soluble Azelaic Acid

Is 60% Water-Soluble Azelaic Acid suitable for sensitive skin?

Yes, azelaic acid is generally well-tolerated across skin types, including sensitive skin. Its mechanism of normalizing keratinocyte function rather than causing aggressive exfoliation contributes to its favorable tolerability profile. Formulators often include it in products designed for reactive or easily irritated skin.

Can this ingredient be combined with other cosmetic actives?

60% Water-Soluble Azelaic Acid can be formulated alongside various other cosmetic ingredients. Its pH range of 4.0 to 6.8 provides compatibility with many common skincare actives. Formulators should conduct stability testing when combining with new ingredient systems to verify compatibility.

What is the difference between water-soluble azelaic acid and regular azelaic acid?

Regular azelaic acid has limited solubility in water, which can restrict its use in clear aqueous formulations and may affect skin penetration. The water-soluble form uses encapsulation technology to improve dispersibility in water-based systems and support enhanced delivery to the skin.

Does this product comply with cosmetic ingredient safety standards?

The ingredient meets the specifications listed in the technical data sheet, including heavy metal limits of ≤10ppm. It is intended for use as a cosmetic ingredient in accordance with applicable regulations. Commercial users should verify compliance with local regulatory requirements for their specific product categories and markets.

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