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Hydroxypropyl Beta Cyclodextrin (HPBCD) Aqueous Solution is a pre-dissolved liquid formulation of hydroxypropyl-beta-cyclodextrin, a cyclic oligosaccharide derivative produced by substituting hydroxyl groups at the C2, C3, and C6 positions of beta-cyclodextrin with hydroxypropyl groups. With a solid content ranging from 45.5% to 55.5%, this ready-to-use solution eliminates the dissolution step in manufacturing processes, reducing production time and operational costs for industrial clients.
The non-reducing molecular structure of HPBCD contributes to its stability in alkaline environments. This colorless to slightly yellow liquid maintains consistent performance across a pH range of 10.5 to 13.5, with residual beta-cyclodextrin content controlled below 0.20%. The high water solubility of HPBCD—exceeding 50% at room temperature—distinguishes it from native beta-cyclodextrin and enables its use in various liquid formulations.
ITEMS | CRITERIA |
|---|---|
pH | 10.5-13.5 |
Residual Beta-Cyclodextrin | ≤0.20% |
Residue on Ignition | ≤2.0% |
Heavy Metals | ≤20ppm |
Solid Content | 45.5%-55.5% |
Appearance | Colorless to slightly yellow liquid |
Property | Value |
|---|---|
Chemical Name | Hydroxypropyl Beta Cyclodextrin Aqueous Solution |
CAS Number | 128446-35-5 |
Molecular Formula | C42H70-nO35(C3H7O)n |
Molecular Weight | 1134.98 + 58n |
HPBCD aqueous solution serves as a solubilizing agent and excipient in pharmaceutical manufacturing. Its molecular encapsulation capability allows it to form inclusion complexes with poorly water-soluble active pharmaceutical ingredients (APIs), enhancing their solubility and bioavailability. The pre-dissolved format supports direct integration into liquid dosage forms, injectables, and ophthalmic preparations without additional dissolution equipment.
Beyond pharmaceutical settings, HPBCD solution functions in battery material formulations where its stabilizing properties support consistent electrolyte performance. It also finds use in daily chemical products as a carrier for active ingredients, helping to improve stability and control release profiles in various personal care formulations.
The HPBCD aqueous solution is supplied in 1000kg food-grade polyethylene drums, designed for efficient handling in commercial procurement and bulk manufacturing operations. Each drum is sealed to prevent contamination and maintain product integrity during transit and storage.
Preserve in well-closed containers. Store in a cool, dry area away from direct sunlight and strong oxidizing agents. Under proper storage conditions, the solution maintains its specified quality parameters throughout its shelf life.
Products are delivered by sea freight for international orders, with standard export packaging procedures applied to ensure safe transportation. Lead times vary based on order volume and destination requirements.
Standard lead times depend on order volume and current inventory levels. Most orders are processed within 7-15 working days after confirmation.
Yes, formulation adjustments such as concentration modifications or pH tuning can be discussed based on commercial users' specific requirements and order quantities.
Production follows established quality management systems. Each batch undergoes testing for pH, solid content, residual beta-cyclodextrin, heavy metals, and residue on ignition before release. Batch records and test reports are available upon request.
Samples are available for evaluation purposes. Recipients cover shipping costs, which may be deducted from subsequent formal orders. Contact our team to arrange sample delivery and discuss testing protocols.
Standard payment terms include T/T for regular orders. For smaller quantities, Western Union and PayPal arrangements are also available. Specific terms can be discussed during the quotation process.
