Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0

Betadex Sulfobutyl Ether Sodium for Injection is a polysubstituted derivative of natural beta cyclodextrin. Sulfobutyl Ether Beta Cyclodextrin Sodium 182410-00-0 Injection Grade is an anionic highly water-soluble cyclodextrin derivative obtained by the substitution reaction of 1,4-butanesulfonolactone with hydroxyl groups on the 2-, 3 -, 6-carbon of beta cyclodextrin under alkaline conditions.

Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 exists in the form of ions after glomerular filtration, and the renal tubular reabsorption is reduced, which prevents the concentration and reabsorption of sbecd in the kidney and weakens the potential damage to the kidney.

The inclusion complex formed with Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 has many applications in pharmaceutical preparations: enhancing the water solubility and bioavailability of insoluble drugs; Masking the bitterness of active ingredients makes it possible to chew and develop orally disintegrating tablets; Increase drug stability and avoid light, heat and oxidative degradation.

In pharmacy, Betadex Sulfobutyl Ether Sodium for Injection is mainly used to increase drug solubility, improve drug stability, promote drug absorption, reduce the stimulation of drugs on the body, as the carrier of sustained-release and targeted preparations.

1. Application of Sulfobutyl Ether Beta Cyclodextrin Sodium 182410-00-0 Injection Grade in injection drugs

When Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 is used for injecting drugs, its solubilizing effect on insoluble drugs is mainly used, so that drugs can be transferred quickly and the required dose can be reached quickly, so as to reduce the stimulation of drugs to the drug delivery site. It can improve the stability of drugs in solution state, reduce the hemolysis effect of drugs, and improve the safety of drug use.

2.Application of Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 in oral medicine

The purpose of using Beta-Cyclodextrin Sulfobutyl Ether Sodium (182410-00-0) for oral drugs is to improve the biological activity of drugs by using its solubilization, increase the release time of drugs in vivo by modifying the release site of drugs, and increase the stability of drugs; It can reduce the irritation of drugs to intestines and stomach, and at the same time, it can cover up the unpleasant smell of some drugs, and improve the feeling of patients taking drugs.

3. Application of Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 in nasal administration

Reduces pain compared to injections. And mainly used as nasal infiltration enhancer, oleic acid stabilizer, co-solvent, improve the infiltration enhancer effect, increase the release of drugs from aqueous solution; To improve the metabolic rate of drug delivery target, currently there is a drug - midazolam using SBE-β-CD as solvent and stabilizer.

4.Application of Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 in ocular administration

The main hope is to increase the solubility of the drug, thus reducing the drug on the corneal stimulation and eye congestion. In some cases, it can also increase the viscosity of ophthalmic drugs, prolong the time of corneal residue, and improve the efficacy of drugs.

5. Application of Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 as chiral additive

As charged cyclodextrin, SBE-β-CD is also a promising chiral additive, which can be used in capillary electrophoresis, chiral membrane resolution and chiral liquid chromatography. However, the application of Betadex Sulfobutyl Ether Sodium CAS NO 182410-00-0 in traditional Chinese medicine is still rare.

Packing Detail : Internal packing: packed PE bag, then put into aluminum foil bag

Outer packing: packed in drum.

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Storage:Preserve well-closed containers protect from moisture.

Packing: 100g/bag ,1kg/bag , 2kg/bag, 10kg/bag/drum ,20kg/bag/drum

Stock: Yes

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Loading location: factory of Binzhou Zhiyuan(China)

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