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Betadex Sulfobutyl Ether Sodium Salt

Betadex Sulfobutyl Ether Sodium Salt is commonly used in insoluble drugs such as voriconazole, carfisomib, ziprasidone, aripiprazole, maloppitant (actin drug), posaconazole, carbamazepine, melphalam, drafloxacin, mebendazole, topiramate, omeprazole, clopidogrel, Docetaxel, sofibuvir, ziprasidone mesylate, L-phenylalanine nitrogen mustard, meloxicam, tetrahydrogestrel, and several other nitrogen-containing API bases are in various stages of incubation.
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Quick Details

Name

Betadex Sulfobutyl Ether Sodium Salt

CAS No.

182410-00-0

DMF No.

030167

Molecular Formula

C42H70-nO35 (C4H8O3SNa)n

Molecular Weight

1135+158n

Appearance

White powder, sweet, insipid and innocuous

Assay

95.0%-105.0%

Classification

Injection Grade


Product Introduction

Β-Cyclodextrin Sulfobutyl Ether is the product of the substitution reaction between β-CD and 1, 4-butane sulfolactone. The substitution reaction can take place on the 2, 3, and 6 carbon hydroxyl groups of the β-CD glucose unit, theoretically leading to a β-CD derivative with a maximum degree of substitution of 21. However, due to steric hindrance and reaction conditions, the maximum degree of substitution is generally less than 10.

β-cyclodextrin sulfobutyl ether 182410-00-0 is white or off white amorphous solid powder with solubility > 50g in 100ml water. The pH of 30% aqueous solution is 5.4~6.8. The relationship between relative molecular weight and degree of substitution is MW = 1135.01 + CDs × 157.99, CDs is the degree of substitution.

Betadex Sulfobutyl Ether Sodium CAS182410-00-0 DMF

Application

Whether in injection or oral medicine, Bate-Cyclodextrin Sulfobutyl Ether USP is a good stabilizer and solvent. In eye drops, when the inclusion complex is formed with the drug, the inclusion complex slowly releases the free drug in the eye, thus reducing the local concentration of the free drug, reducing or eliminating the irritation to the eye caused by the rapid absorption or precipitation of the drug. For the negatively charged Betadex Sulfobutyl Ether Sodium Salt, the charged state of the encapsulated drug affects its inclusion ability, and the binding force with the positively charged drug is stronger, and the stability constant of the inclusion complex is larger.


Delivery

On-demand pack size is available without surcharge.

This Product is available in multi-kilograms pack size, such as: 1kg,5kg,10kg

Internal packing: PE bag and aluminum foil bag

Outer packing: carton or drum.

Storage:Preserve well-closed containers protect from moisture.

Shipping Information

Tariff No.:3505100000


FAQ

1. What's the main advantanges about your factory?

We have a professional product research and development team,the most advanced production line and detecting instruments, sales team with humanistic service(including after-sale service).Conforms to GMP standand and meets USP,EP

2. What’s the quality assurance you provided and how do you control quality?

  • Established a procedure to check products at all stages of the manufacturing process-raw materials, process materials, validated or tested materials finished goods etc. Besides, we have also developed a procedure which identifies the inspection and test status of all stages of the manufacturing process.

  • 100% inspection in assembly lines. All controls, inspection, equipment, fixtures, total production resources and skills are inspected to ensure they consistently achieve the required quality levels. our product is under the supervision of QA and QC,firmly conforms to GMP standard.

3. Can I know your MOQ and delivery time?

Our Minium Order Quantity is 1Kg, products can be sent within one week after payment confirmed.

4. Can purchaser come to audit?

We warmly welcome customers' audit,it's an effective way to build a better business relationship.


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