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| Quantity: | |
|---|---|
| Quick Details |
Name | Hydroxypropyl gamma cyclodextrin (HP-γ-CD) |
CAS No. | 128446-34-4 |
Molecular Formula | C48H80-nO40.(C3H7O)n |
Molecular Weight | 1297.2+n.(58.1) |
Appearance | white powder, insipid, innocent |
Assay | ≥98％ |
Classification | Pharmaceutical Grade |
quality standard | Enterprise Standard |
| Product Introduction |
Hydroxypropyl gamma cyclodextrin (HP-γ-CD) is a derivative of gamma Cyclodextrin. It can crosslink to form longer polymers. It is a very useful chemical for Supramolecular chemistry. Other application field: solubilizing macromolecules, cultivating cells, etc. It is similar to beta cyclodextrin, but it can interact with larger molecules.
Hydroxypropyl gamma cyclodextrin manufacturer-Shandong Binzhou Zhiyuan Biotechnology Co., Ltd which has completed registration with FDA, and the registration information is as follows:
Company name: Shandong Binzhou Zhiyuan Biotechnology Co., Ltd
FDA ESTABLISHMENT IDENTIFIER (FEI No.)：3011680310
ESTABLISHMENT ADDRESS: Boxing Economic Development Zone,, Binzhou, Shandong 256500, China (CHN)
DUNS: 548171477
| Features |
Hydroxypropyl)-γ-cyclodextrin 's water solubility increase to 80g/100ml (25 C) furtherly , and hydroxypropyl gamma cyclodextrin is no longer a single pure product but the coexistence of multiple substituted compounds, with guest molecules when wrapping is not easy to generate inclusion crystallization. Overall, hydroxypropyl- gamma cyclodextrin has a higher solubility in water and stronger anti crystallization ability.
| Specification |
Test Standard | Enterprise standard |
ITEMS | SPECIFICATION |
Appearance | white powder, insipid, innocent |
Assay | ≥98％ |
Absorbance | the absorbance at 230~350nm should not exceed 0.50, while at 350~660nm should not exceed 0.5 |
PH | 6.0 ~ 9.0 |
Loss on Drying | ≤10.0％ |
Gamma cyclodextrin | ≤1.5％ |
Propylene glycol | ≤0.5％ |
Residue on Ignition | ≤0.2％ |
Heavy Metal | ≤10ppm |
Molar Substitution | 0.5-0.7 |
Microbiology | |
Aerobic microorganism | ≤1000CFU/g |
Moulds & yeasts | ≤100CFU/g |
Escherichia Coli | Absence |
| Application |
In the field of Pharmaceutical：
Hydroxypropyl gamma cyclodextrin (HP-γ-CD) can enhance drug solubility, stability, and bioavailability.
It can controlled release of encapsulated substances.
It can regulate the release rate and time of the drug to achieve better therapeutic effect In the drug delivery system.
Solubilization and solubilization, anti-oxidation, odor, slow release, targeted drug delivery, etc.
| Packing & Storage |
Packing Detail :
Internal packing: packed PE bag, then put into aluminum foil bag
Outer packing: packed in carton or drum.
Label according to customers' request.
Storage:
Preserve well-closed containers protect from moisture.
| Delivery |
Stock: Yes
Delivery : Delivery goods within 1-3 workdays.
Loading location: factory of Binzhou Zhiyuan(China)
We can supply DDU service,FOB, CFR, or CIF service;
For high value products, please select air shipping and express delivery for safety.
| Certificate |
FAQ |
Do you accept sample order?
We accept sample orders.MOQ: 0.1kg.
How to confirm the product quality before placing orders?
It is recommended to test the quality of the samples before placing an order, as we can ensure that the quality of the order is consistent with the quality of the samples.
Do you supply product report?
Yes. We'll give you product analysis report before shipping.
Is there a discount?
uDifferent quantity has different discount.
Application Case |
In olopatadine hydrochloride Ophthalmic Solution, Hydroxypropyl gamma cyclodextrin (HP-γ-CD) is the best forming agent.
Olopatadine eye drops are solution agents, which are used to treat signs and symptoms of allergic Conjunctivitis. It can be used for the treatment of bacterial Conjunctivitis, Keratitis, dacryocystitis, postoperative infection and other external eye infections.
Hydroxypropyl gamma Cyclodextrin can significantly enhance the solubility of Olopatadine in aqueous solution, reduce the bitterness of Olopatadine, and greatly improve the stability of olotadine. Because of the inclusion effect of hydroxypropyl gamma Cyclodextrin on Olopatadine, Olopatadine can be slowly released, which can increase the administration time in the actual administration process.
